The Rosie Project by Graeme Simsion is a novel told in first person about a man's search for the perfect wife -- otherwise known as the Wife Problem. Don Tillman, the protagonist, is a genetics professor. He has decided it is time to find a wife. And like most of his life, he goes about this in a very scientific, structured way. As Don admits, he does not think the same way as most people. He starts his search for his perfect mate by designing a survey to post online.
If you like this book, you may also enjoy The Curious Incident of the Dog in the Night-Time.